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BACKGROUND: Totally implantable venous access port system (Port-A-cath) is widely used in pediatric cancer patients. However, port-A-cath is not free of complications that may necessitate device removal and consequently delay in chemotherapy. OBJECTIVE: In this study, we investigated the indications for Port-A-cath removal and the underling possible risk factors, that may predispose to premature removal (i.e. removal before completion of therapy), such as the type of cancer and clinical parameters. METHODS: The study is a retrospective review of port-A-cath removal in pediatric hematology-oncology patients during the period from January 2011 to December 2013. 106 patients were included in the study among which 6 were excluded. Data were collected by reviewing patients’ files, with supplementation from electronic patient’s records. RESULTS: Over three years period, 100 port-A-cath were removed. The indications of removal were completion of therapy 74 (74%), infection 20 (20%), malfunction (blockage) 5 (5%) and mechanical complications 1 (1%). Cross table analysis of data showed that young age (less than 5 years of age) is the only significant risk factor P-value less than 0.05, with no other significant risk factor that independently contribute to the premature removal of port-A-cath. CONCLUSION: We observed that risk factors are interdependent in predisposing to port-A-cath complications and hence early removal. Following standardized meticulous surgical techniques and proper maintenance care are appropriate strategies to prevent infection and other complications. Key word: Port-A-cath, hem-oncology, pediatric.

Risk Factors Affecting the Longevity of Totally Implantable Access Ports in Pediatric Cancer Patients