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TB (Tuberculosis) of intrathoracic lymph nodes is the most common form of tuberculosis disease in childhood. In Bulgaria, about 67%-70% of all newly diagnosed children patients are with this diagnosis. The purpose of this study was to determine the diagnostic capabilities of the T-SPOT TB in this form of TB disease. In a period of one year, 50 children aged 0-12 years treated in our hospital with tuberculosis of lung lymph nodes were examined. The diagnosis was set based on history, clinical, microbiological and radiological check. T-SPOT TB (ELISPOT TB test) and the TST (tuberculin skin test) were performed simultaneously on the studied children. The relationship between immunological samples TST and T-SPOT TB (presence of BCG vaccination and contact with adult TB patient). One child had TST negative samples, 32% had normergic reactions to 15mm. 66% had hyperergic above 15mm. In a study with T-SPOT TB, 28% showed negative results and 72% showed positive.

Comparison of T-SPOT TB and Tuberculin Skin Test in Children with Tuberculosis of Intrathoracic Lymph Nodes