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Restless legs syndrome (RLS) is characterized by discomfort in the legs, which might be creeping, crawling, tingling, or painful in nature.1 These symptoms are worse at rest, are relieved by movement, and mainly occur in the evening or night. Because of this, RLS patients complain that they have difficulty in falling asleep or maintaining sleep.2,3 Additionally, these symptoms are connected to fatigue, depressive mood, damaged working ability, and social isolation.4,5 Epidemiological studies have demonstrated that the symptoms of RLS are present in about 5-10% of the general population.2,6 Nevertheless, proper treatment has not always been conducted for the symptoms of RLS because of low recognition or under diagnosis of the disease.7 To widen knowledge of the syndrome in Korea, more clinical experience and studies are necessary. There have been few studies in Korea in which idiopathic RLS patients have been studied for clinical features. This study was therefore conducted to determine the severity level of patients with RLS by using the RLS severity scale developed by the International RLS Study Group (IRLSSG), and to further examine the relationships between RLS severity and sleep quality, daytime sleepiness and depression. In addition, iron metabolism changes and nocturnal polysomnography (NPSG) characteristics were studied.

A Single Center Study of the Clinical Features and Comorbidities of Patients with Restless Legs Syndrome