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Recurrent oral herpes labialis (ROHL) is a rather widespread oral ulcerative condition with an unclear etiology. The clinical characteristics of ROHL have been defined and therapies include systemic drugs and topical application of ointment to the lips. However, these approaches have not been rigorously evaluated. Persistent, painful ROHL was successfully treated with fucoidan in two patients. This study investigated the time required to complete healing and loss of discomfort. Two patients used Power Fucoidan CreamTM (PFC) (4% fucoidan cream). ROHL was markedly improved by Power Fucoidan Cream in terms of both time to healing and time to loss of discomfort. Further clinical trials are needed to confirm the value and safety of topical Power Fucoidan Cream for treating ROHL.

dentistry

Case Report Using 4% Fucoidan Cream for Recurrent Oral Herpes Labialis: Patient Symptoms Markedly Improved in Terms of Time to Healing and Time to Loss of Discomfort