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Justifi cativa e Objetivos: : O controle de infeccoes relacionadas a assistencia a saude em neonatos representa um desafi o e um sistema de vigilância ativa e essencial defi nir medidas preventivas. Este estudo tem como objetivo descrever as principais topografi as e indicadores de infeccoes relacionadas a assistencia a saude em Unidade Neonatal conforme os criterios de vigilância epidemiologica estabelecidos pela Agencia Nacional de Vigilância Sanitaria. Metodos: Trata-se estudo transversal, observacional, prospectivo, realizado de 2009 a 2010. Foram incluidos todos os pacientes sob risco e a notifi cacao de infeccoes seguiu os criterios recomendados pela Agencia Nacional de Vigilância Sanitaria. Analise estatistica, com calculo da densidade de incidencia de infeccoes, frequencia e percentual de microrganismos, mortalidade, letalidade e densidade de incidencia de infeccoes associadas a procedimentos invasivos. Resultados: Foram acompanhados 609 neonatos sob risco, totalizando 13.215 pacientes-dia no periodo. A densidade incidencia de infeccao foi de 26,3 por 1000 pacientes-dia, predominando infeccao de corrente sanguinea (58,8%). Em 116 (33,4%) casos de infeccoes notifi cadas, houve isolamento de microrganismo, predominando Staphylococcus coagulase negativo. Conclusao: Os principais indicadores de infeccoes e topografi as foram semelhantes a outros estudos conduzidos previamente. A defi nicao de parâmetros de vigilância epidemiologica de infeccoes relacionadas a assistencia a saude em nivel nacional e fundamental para o planejamento de acoes com o objetivo de prevenir estes agravos em populacoes suscetiveis como neonatos. Backgound and Objectives: Healthcare Associated Infections in neonates represent a challenge and an active surveillance system is essential to develop preventive measures. This study aims to describe the main sites and data of Healthcare Associated Infections according to the criteria defi ned by National Agency for Sanitary Surveillance at a reference Neonatal Unit. Methods: This is a prospective observational study conducted from 2009 to 2010. We included all patients at risk and notifi cation of infections followed criteria defi ned by Agencia Nacional de Vigilância Sanitaria. For Statistical analysis, we calculated the incidence density of Healthcare Associated Infections, frequency and percentage of microorganisms, mortality, and incidence density of deviceassociated infections. Results: This study followed 609 newborns, with 13,215 patient-days. Incidence density of infection was 26.3 per 1000 patient-days, predominantly bloodstream infection (58.8%). microorganisms were isolated, in 116 (33.4%) cases, predominantly coagulase negative Staphylococcus. Conclusion: The main sites and data of IRAS were similar to other previous studies. The defi nition of parameters for national surveillance of Healthcare Associated Infections is critical for planning actions in order to prevent these diseases in susceptible populations as neonates.

NOTIFICAÇÃO DE INFECÇÕES EM UNIDADE NEONATAL COM CRITÉRIOS NACIONAIS