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Deficit and imbalance of Ca2+ and Mg2+ can be considered as potential risk factors for urolithiasis, skin diseases, cardiovascular system and digestive organs [5-9]. One of the main effectors of homeostatic regulation of magnesium and calcium balance are kidneys [10-14], while data on the impact of excess Ca2 + and Mg2+ in drinking water on the functional state of various organs and systems of the growing organism are much less [15].

Physical Development and Renal Functions in Adolescents Consuming Drinking Water with High Content of Vital Cation