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Background: Dyslipidemia is frequent in obese patients. Long-term outcomes of dyslipidemia after bariatric surgery have not been reported. Our aim is to report long-term evolution of dyslipidemia after bariatric surgery, comparing laparoscopic Roux-Y gastric bypass (LRYGB) versus sleeve gastrectomy (LSG). Methods: Retrospective analysis between 2001 and 2010. Demographics, comorbidities, lipid profiles and excess weight loss (%EWL) at 5 years were retrieved, comparing values and dyslipidemia remission after LRYGB and LSG. Results: 2.416 LRYGB and 1.408 LSG patients were included. Basal demographics and comorbidities were similar between groups, except for higher body mass index in LRYGB patients. 152 LRYGB and 94 LSG patients achieved 5 years follow-up, reaching 83% and 70% EWL, respectively (p<0.01). Long-term dyslipidemia remission for LRYGB and LSG was achieved in 60% and 25% for total cholesterol; 80% and 57% for LDL-cholesterol; 80% and 92% for low HDL-cholesterol and 74% and 59% for triglycerides, respectively. Multivariate analysis showed that total cholesterol and triglycerides were significantly lower in LRYGB patients (p<0.05) at the fifth year. LDL-cholesterol and HDL-cholesterol showed no differences between groups (p=0.08 and 0.33, respectively). Conclusion: At long-term, bariatric surgery reach an acceptable remission or improvement of dyslipidemia, especially for total cholesterol and triglycerides after LRYGB compared to LSG.

Long-term Results of Dyslipidemia after Bariatric Surgery: A Comparison between Gastric Bypass and Sleeve Gastrectomy