English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

In Computed Tomography (CT) the selection criteria for Hounsfield unit (HU) at vertebral body (VB) for the diagnosis of bone mineral density (BMD) disease are variable. The purpose of our study is to determine the correlation between T-score from a dual-energy X-ray absorptiometry (DXA) scan and HU values at different ROIs across the VB at L1 to L4 for the assessment of BMD disease. 114 women who had both a CT scan abdomen and DXA scan within one year were enrolled in the study. Different ROIs for HU measurements were obtained throughout L1 to L4, the lowest HU, HU at central portion of the VB; and the average of 3HU values across the VB. Statistical analysis was used to compare the performance of the different HU values for the diagnosis of BMD disease, and the correlations with the T-score. There was a moderate correlation between the T-score and HU value at different ROIs, (r 0.597, 0.615, 0.591) (P value<0.001). HU with 95% sensitivity for diagnosis of osteoporosis were 116, 123, 130 and 95% specificity were 173, 177, 181 for the lowest, central and the average of three axial slices, respectively. No statistical difference in the mean HU at L1 from the average mean of L1–L4. In conclusion the homogenous HU distribution across the VB throughout the lumbar spine and L1 will allow more flexibility in the selection of the ROI for HU values for BMD disease.

Regional Differences of Hounsfield Unit in the Diagnosis of Bone Mineral Density Disease