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Address for Correspondence: Dr. Gayatri. N, Associate Professor of Anatomy, MNR Medical College and Hospital, Sangareddy, Telangana, India. Mobile no: +919866084854. E-Mail: drgayatri1884@gmail.com Background: Cortical folding is a hallmark of many but not all mammalian brains. The degree of folding gradually increases with the size of brains in mammals but at different range between the families.Gyrification is a process which varies widely in mammals in early foetal and prenatal life. Materials: This study was conducted on 100 dead foetuses in anatomy department, brought from the department of Obstetrics and gynaecology of MNR Medical College and Hospital. Results: The brain surface is smooth up to 12 weeks,Cingulate sulcus appeared by 16-18weeks.Growth of adjoining lobes of brain make surface more convoluted with well-defined sulci and gyral pattern between 30-32 weeks. Conclusion: Cortical folding is due to consequence of restricted space and rapid growth of brain with in the cranial cavity. There is no differences between male and female brains of same gestational age, with no obvious asymmetrical development of gyri on different lobes of brain.

CORTICAL FOLDING ON MEDIAL SURFACE OF FOETAL BRAIN AT DIFFERENT GESTATIONAL AGE