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Address for Correspondence: Dr Shabna C, Senior Resident, Department of Anatomy, Government medical college Calicut, Kerala, India. Pin 673008 E-Mail: drshabnac@gmail.com Background: Recently there has been growing interest in the duct system of pancreas as concerns its relationship with various disease processes as well as newer investigatory and treatment modalities related to them.This study has been aimed at evaluating the anatomy of the pancreatic duct system, thus identifying the variants to improve our knowledge of it and make things easier. The pancreas is formed by the fusion of the ventral and dorsal anlage, and a wide spectrum of anomalies or anatomical variations may appear related to this complicated process of fusion: e.g., agenesis, aplasia of a pancreatic anlage, hypoplasia, annular pancreas, pancreas divisum or nonfusion of the ventral and dorsal duct system, pancreaticobiliary maljunction, etc. Every endoscopist who engages in pancreatography or related diagnostic and therapeutic procedures should always be aware of all sorts of anatomical variations he or she might encounter. Materials and Methods: The pancreatic duct system of 50 adult human specimens were demonstrated by casting with acrylic resin using postmortem preparations Results: The normal anatomic variants of the main pancreatic duct(duct of Wirsung) and accessory pancreatic duct(duct of Santorini) have been shown. In 52% of specimens, the major pancreatic duct followed the usual pattern and opened into the major duodenal papilla. Accessory pancreatic ducts were present in 48 % of the cases. Variations in patterns of the main duct, collecting ducts, ductules have been noted. Patterns related to certain conditions of pancreas were noted. No herring bone pattern was observed. The pancreatic duct system was classified. Conclusion: From the present study, it is concluded that knowledge of variation of pancreatic duct system can be used treatment of various diseases like pancreatitis pancreatic necrosis, or acute pancreatic fluid collections, chronic pancreatic fistulae and during procedures like ERCP, MRCP, EUS–guided pancreaticogastrostomy (EPG), transpapillary endoprostheses, Resective or decompressive pancreatic surgery etc.

VARIATIONS IN THE DUCT SYSTEM OF PANCREAS: A CADAVERIC STUDY