Open AccessHumoral Response after SARS-CoV-2 mRNA Vaccination in a Cohort of Hemodialysis Patients and Kidney Transplant Recipients
Author(s) -
Clément Danthu,
Sébastien Hantz,
Arthur Dahlem,
Marion Duval,
Bacary Bâ,
Ma Guibbert,
Zhour El Ouafi,
Séverine Ponsard,
Insaf Berrahal,
Jean-Michel Achard,
F. Bocquentin,
Vincent Allot,
JeanPhilippe Rerolle,
Sophie Alain,
Fatouma Touré
Publication year - 2021
Publication title -
journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.451
H-Index - 279
eISSN - 1533-3450
pISSN - 1046-6673
DOI - 10.1681/asn.2021040490
Subject(s) - medicine , seroconversion , vaccination , serology , hemodialysis , interquartile range , immunology , antibody titer , kidney transplantation , titer , antibody , concomitant , transplantation , gastroenterology
Kidney transplant recipients and patients receiving hemodialysis are immunocompromised populations that are prioritized for COVID-19 vaccination but were excluded from clinical trials of SARS-CoV-2 mRNA vaccines. Antibody titers and rates of seroconversion after vaccination are lower among patients with CKD and those taking immunosuppressants compared with controls. Data are lacking regarding their humoral response to vaccination to prevent COVID-19.
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