Open AccessUltrastructural Evidence for Direct Renal Infection with SARS-CoV-2
Author(s) -
Evan A. Farkash,
Allecia M. Wilson,
Jeffrey M. Jentzen
Publication year - 2020
Publication title -
journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.451
H-Index - 279
eISSN - 1533-3450
pISSN - 1046-6673
DOI - 10.1681/asn.2020040432
Subject(s) - medicine , kidney , pathology , autopsy , acute kidney injury , kidney disease , nephrology , coronavirus , covid-19 , disease , infectious disease (medical specialty)
A significant fraction of patients with coronavirus disease 2019 (COVID-19) display abnormalities in renal function. Retrospective studies of patients hospitalized with COVID-19 in Wuhan, China, report an incidence of 3%-7% progressing to ARF, a marker of poor prognosis. The cause of the renal failure in COVID-19 is unknown, but one hypothesized mechanism is direct renal infection by the causative virus, SARS-CoV-2.
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