A Peripheral Blood Gene Expression Signature to Diagnose Subclinical Acute Rejection | Zendy

Weijia Zhang | Zendy; Zhengzi Yi | Zendy; Karen Keung | Zendy; Huimin Shang | Zendy; Chengguo Wei | Zendy; Paolo Cravedi | Zendy; Zeguo Sun | Zendy; Caixia Xi | Zendy; Christopher Woytovich | Zendy; Samira Farouk | Zendy; Weiqing Huang | Zendy; Khadija Banu | Zendy; Lorenzo Gallon | Zendy; Ciara N. Magee | Zendy; Nader Najafian | Zendy; Milagros Samaniego | Zendy; Arjang Djamali | Zendy; Stephen I. Alexander | Zendy; Ivy A. Rosales | Zendy; R. Neal Smith | Zendy; Jenny Xiang | Zendy; Evelyne Lerut | Zendy; Dirk Kuypers | Zendy; Maarten Naesens | Zendy; Philip J. O’Connell | Zendy; Robert B. Colvin | Zendy; Madhav C. Me | Zendy; Barbara Murphy | Zendy

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A Peripheral Blood Gene Expression Signature to Diagnose Subclinical Acute Rejection

Author(s) -

Weijia Zhang,

Zhengzi Yi,

Karen Keung,

Huimin Shang,

Chengguo Wei,

Paolo Cravedi,

Zeguo Sun,

Caixia Xi,

Christopher Woytovich,

Samira Farouk,

Weiqing Huang,

Khadija Banu,

Lorenzo Gallon,

Ciara N. Magee,

Nader Najafian,

Milagros Samaniego,

Arjang Djamali,

Stephen I. Alexander,

Ivy A. Rosales,

R. Neal Smith,

Jenny Xiang,

Evelyne Lerut,

Dirk Kuypers,

Maarten Naesens,

Philip J. O’Connell,

Robert B. Colvin,

Madhav C. Me,

Barbara Murphy

Publication year - 2019

Publication title -

journal of the american society of nephrology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 4.451

H-Index - 279

eISSN - 1533-3450

pISSN - 1046-6673

DOI - 10.1681/asn.2018111098

Subject(s) - subclinical infection , peripheral blood , medicine , signature (topology) , gene expression , gene signature , peripheral , gene , immunology , biology , genetics , mathematics , geometry

In kidney transplant recipients, surveillance biopsies can reveal, despite stable graft function, histologic features of acute rejection and borderline changes that are associated with undesirable graft outcomes. Noninvasive biomarkers of subclinical acute rejection are needed to avoid the risks and costs associated with repeated biopsies.

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