Open AccessNephron Remodeling Underlies Hyperkalemia in Familial Hyperkalemic Hypertension
Author(s) -
James A. McCormick,
David H. Ellison
Publication year - 2017
Publication title -
journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 4.451
H-Index - 279
eISSN - 1533-3450
pISSN - 1046-6673
DOI - 10.1681/asn.2017060660
Subject(s) - hyperkalemia , medicine , nephron , intensive care medicine , cardiology , kidney
The molecular unraveling of Mendelian diseases often reveals previously unknown physiologic control systems. The molecular solution of Familial Hyperkalemic Hypertension (FHHt; also known as pseudohypoaldosteronism type 2 or Gordon syndrome) uncovered a complex signaling network in the mammalian
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