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In the previous paper, the author, with normal, adult dogs, has described his findings on general shapes and forms of hypothalamic neurosecretory cells, cell nucleus, mitochondria, GOLGI apparatus, NISSL substance, and secretory material together with their correlations in various phases of secretory cycle. The author, however, has felt as a result of the previous researches, that there are many problems still left undetermined by the mere findings on the normal-conditioned animal. Generally, in cytological studies on glandular cells, not only the findings on normal conditions, but those on various experimental conditions esp. those under physiological conditions which accelerate glandular activities should be noted and the comparison between both these findings has very often proved to be of much use for the interpretation of secretory process. The neurosecretory material is a histological indicator of the posterior lobe hormone with adiuretin as its chief functional substance which, in the experimentally dehydrated condition, that is, in the condition that demands antidiuretic hormone, decreases markedly, and yet recovers itself when water is given. This has been reported by several investigators, and the author et al. (TAMIYA, IMOTO and TAKAHASHI 1956) have as well confirmed its findings by staining the neurosecretions and reported on it. Very few researches, however, have been carried out on the cytological findings on neurosecretory cells in the dehydrated conditions. Following the previous paper in which the author has reported on the cyto-organelles in the neurosecretory cell in the normal condition, the present paper describes the author's subsequent cytological studies on the neurosecretory cell in the dehydrated condition, that is, the condition of an excited secretory activity.

archivum histologicum japonicum

Neurosecretory System in Experimental Condition. IV. Cytological Findings on the Hypothalamic Neurosecretory Cells of the Experimentally Dehydrated Dog