Open AccessIs Targeting the Folate Receptor in Ovarian Cancer Coming of Age?
Author(s) -
Birrer Michael J.,
Betella Ilaria,
Martin Lainie P.,
Moore Kathleen N.
Publication year - 2019
Publication title -
the oncologist
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.176
H-Index - 164
eISSN - 1549-490X
pISSN - 1083-7159
DOI - 10.1634/theoncologist.2018-0459
Subject(s) - medicine , folate receptor , ovarian cancer , epithelial ovarian cancer , cancer , receptor , oncology , cancer research , bioinformatics , cancer cell , biology
Prognosis for women with epithelial ovarian cancer remains poor. One new molecular target in epithelial ovarian cancer is folate receptor alpha (FRα). This commentary discusses the characteristics that contribute to its attractiveness as a candidate for therapeutic intervention.