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ハトムギの種皮を除いた種子の部分であるヨクイニンは長年疣贅に対する伝統的な漢方薬として利用されているしかしながらハトムギの殻薄皮渋皮の熱水抽出物についての安全性試験に関する報告は少ないそこで我々はハトムギの殻薄皮渋皮種子のすべての部分を含む熱水抽出物を高用量 (2,000 mg/kg) 摂取した場合の 28 日間反復経口投与毒性試験をラットを用いて行ったところ当該エキス摂取後の体重変化血液検査臓器重量測定・組織病理検査尿検査のすべての項目において異常は認められなかったCoix lacryma-jobi L. var.ma-yuen Stapf (coix seed) is a grass crop that has long been used in traditional medicine as a nourishing food. However, high-intake safety of the extract of the husks, pellicles and astringent skin of coix seed has rarely been evaluated. We performed a 28-day repeated dose oral toxicity test of hot water extract of all parts of Coix seed in rats. The extract showed no significant toxicity on body weight, blood analyses, urinalysis and histopathological examination in acute toxicity tests

28-day Repeated Dose Oral Toxicity Test of Coix lacryma-jobi L. var. ma-yuen Stapf in Rats