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VitaminB12 was given in an amount of 25γ per day for a period of one year to children with nutritional dystrophy. A marked rise of blood vitaminB12 levels was reached on the 5th month of the vitaminB12 administration, and thereafter blood vitaminB12 levels showed a decrease in spite of continued doses of the vitamin. Urinary excretion of folic acid was not influenced by the administration of vitaminB12. Urinary output of formiminoglutamic acid was found more frequently even in summer in cases with the vitaminB12 administration than in those without same.

An Aggravation of Folic Acid Deficieney by An Administration of VitaminB<sub>12</sub> upon Children with Nutritional Dystrophy