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In order to elucidate the problem of uterus-sensitivity to ovarian hormones, the following experiments were carried out. 1) The author proposed a new desease “Hyposensitive uterus”, provisionally denominated, and three cases of it were reported. This desease is characterized by irresponsiveness of the uterus to ovarian hormones, regardless of the normal function of ovary, confirmed by typical biphasic B. B. T. curve, normal value of estrogen and pregnanediol excretion in the urine and confirmation of corpus luteum by laparotomy. 2) Various kinds of methods of laboratory testing of uterus-sensitivity were devised to make diagnosis of anomalous sensitivity of uterus. A summation of data examined by these tests leads to the conclusion that uterus-sensitivity test by the measurement of oxygen consumption of endometrium and myometrium was most convenient and valuable in clinical use.

New Methods of Laboratory Testing for the Sensitivith of the Uterus to Ovarian Hormones