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Higashi published “Congenital Gigantism of Peroxidase Granules” in Sept. 1953, in which I was very much interested, because I had not seen any case of such an abnormity during my own 30 years' experience with the peroxidase reaction. Then I happened to read an article published in 1952 by Chediak: Nouvelle anomalie leucocytaire de caractere constitutionnel et familial. On perusal, I came to consider both diseases as two different manifestations of one and the same clinical entity, though there was no description of peroxidase or oxidase raaction in Chediak's paper. So I desire to suggest for this new clinical entity the name: Chediak and Higashi's Disease or Chediak-Higashi's Leuco-anomaly.

Chédiak and Higashi's Disease. Probable Identity of “A New Leucocytal Anomaly (Chédiak)” and “Congenital Gigantism of Peroxidase Granules (Higashi)”