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(From the Medico-chemical Institute, Tohoku University, Sendai) (Received for publication, March 31, 1953) It was found that the Group B lipoid of hog lung1) changes in part into a Group A substance (determined by iso-agglutination inhibition test) on standing in physiological saline. The optimum pH was 7.0, just as for the ƒ¿,ƒÀ-rearrange ment of N-glycosides. The change, which was hardly noticed at 0•Ž, occurred more and more markedly with raising the temperature of the solution, and when the latter was again cooled to 0•Ž, the A activity diminished gradually. That the appearance of A activity is not due to formation of a non-specific anti-agglutinative agent was confirmed by an absorption experiment by the use of anti-A and anti-B agglutinin. Interconversion of Group lipoids A and B of human liver could be caused by procedures different from above. We subjected those group lipoids to partial alkaline cleavage so as to separate a group-potent portion rich in carbohydrate. A spot on a filter

Interconversion of Blood Group Lipoids A and B <i>in vitro</i> and N-Glycoside Linkage in Group Substances A and B in General