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Some experimentalists claimed that the augmentation of adrenaline secretion may be caused by the roentgen irradiation of the adrenal region. Risse and Poosla irradiated the roentgen ray on the upper abdomen of the rabbit, using the pupil sensitized to adrenaline by removing the superior cervical ganglion previously as an indicator of the augmentation of adrenaline secretion. They found after irradiation the dilation of the pupil at first and inferred this dilation to be attributed to the augmenta tion of the adrenaline secretion from the adrenals. Using the suprareno jugular anastomosis method, Zunz and La Barre2) observed the elevation of the blood pressure and the constriction of the spleen in a recipient dog after the roentgen irradiation in a dose of 100-300r on the adrenal region of the donor dog. Further, collecting the adrenal vein blood specimens, they measured the adrenaline content in these blood specimens and observed the increase of adrenaline content after the roentgen irradiation of the adrenal area. The same investigators observed also that the pressor effect of the roentgen irradiation of the adrenal region in rabbits was abolished by the removal of the both adrenal glands. A reduction or an augmentation of the adrenaline content in the ad renal gland caused by the irradiation of roentgen ray was observed by some experimentalists.3) It may be added here that some physicians4) applied the roentgen irradiation of the adrenal region in the treatment of some diseases, assum ing that the roentgen ray has an inhibitory effect on the adrenal glands contrary to the reports above quoted.

Effect of Roentgen Irradiation of the Adrenal Region on the Adrenaline secretion of the Adrenals in Non-anesthetized Dogs