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Contrary to some writers, the present author has never come tb see the existence of epinephrine in the general blood of rabbits, poisoned by the morphine. Both the rabbit intestine segment method and the frog legs vessels method were employed. Exactly said that the epinephrine does not exist in the peripheral blood beyond the limits determinable by means of both the methods. The failure of the previous writers might be explained probably in this way that they did not pay any attention upon the fluctuation of sen-sibility of the vessel perfusion method against epinephrine or adrenaline in the course of experiment. The second writer carried on his experiment on the animal while it was near moribund, or very weakly.

Does the Amount of Epinephrine in the Peripheral Blood after Morphine Exceed the Limits Deter-minable by the Frog Legs Vessels Method