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We devised an improved technique of thin layer chromatography, which permitted the high resolution of urinary neutral oligosaccharides and the qualitative determination of blood group related oligosaccharides as well as oligosaccharides pathologically secreted in lysosomal storage diseases. This procedure can be used inscreening for disorders associated with abnormal excretion of oligosaccharides, as well as in the purification of oligosaccharides.

tohoku journal of experimental medicine

Thin-layer chromatography of urinary neutral oligosaccharides: The detection of blood group-related oligosaccharides and screening for lysosomal storage disease.