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By an indirect immunofluorescence technique using the somatostatin antibody, somatostatin-containing cells were demonstrated to exist in the human, dog and rat thyroids. These cells were located predominantly in the interfollicular areas and more scatteringly in the follicular areas. The source of these somatostatin-containing cells was discussed.

Immunohistochemical demonstration of somatostatin-containing cells in the human, dog and rat thyroids.