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MIYAJI, T. The Effect of Simultaneous and, Alternate Feeding of Furyl furamide and 4-Dimethylaminoazobenzene on Rats. Tohoku J. exp. Med., 1971, 103 (4), 371-379 In view of the remarkable effect of Furylfuramide to induce hypertrophy of liver cells, its possible action as a co-carcinogen or accelerator in hepatic carcinogenesis was examined. However, simultaneous feeding of Furylfuramide and 4-dimethylaminoazobenzene (DAB) inhibited carcinogenesis in the liver by DAB. Protein-bound azo-dye in the liver was reduced in quantity. No inhibitory effect against DAB carcinogenesis was observed when Furylfuramide was fed prior to or after the administration of DAB for various length of time. furylfuramide; 4-dimethylamino azobenzene; carcinogenesis

The Effect of Simultaneous and Alternate Feeding of Furylfuramide and 4-Dimethylaminoazobenzene on Rats