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IsHII, Y., MORI, M. and FUJIMOTO, T. Immunofluorescence Study of Germinal Centers in Mouse Lymph Nodes during the Secondary Immune Response. Tohoku J. exp. Med., 1970, 102(2), 143-157 An immunofluorescence study carried out on the relationship between the mode of localization of antigen and that of specific antibody and ƒÁ-globulin in the germinal centers of mouse popliteal lymph nodes during the secondary immune response. The germinal centers of popliteal lymph nodes from mice sensitized secondarily with antigen (human ƒÁ-globulin) contained both antigen and ƒÁ-globulin in a similar distribution, giving lacy or reticular frame work of immunofluorescene. Specific fixation of heterologous (guinea pig) com