English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Bioresorbable linear poly(ether-ester-urethane)s with different hydrophilic characteristics were\udsynthesized from triblock copolymers of poly(¿-caprolactone)-poly(ethylene oxide)-poly(¿-caprolactone) (PCL-PEO) as macrodiols, and L-lysine diisocyanate (LDI) or hexamethylenediisocyanate (HDI) were used as the required diisocyanates. Macrodiols were obtained by ring-opening polymerization (ROP) of ¿-caprolactone (CL). Polyurethanes were synthesized by the reaction of the triblock copolymers with LDI or HDI in solution using stannous 2-ethylhexanoate as catalyst. Polyurethane tablets were fabricated\udand investigated as prospective drug delivery systems. The effect of the PEO content on the polymers¿ performance as drug carriers was evaluated. It was found that water provoked more swelling and erosion of polymers with higher contents of PEO. The hydrocortisone release profiles were analyzed using the Ritger-Peppas approximation. An anomalous release behaviour (values of n higher than 0.5) was found for most of the analyzed samplesWe acknowledge the financial support provided\udby the Consejo Nacional de Ciencia y Tecnología\ud(CONACYT), México, Ministerio de Ciencia e Innovación\ud(MAT2014-52644-R), Spain, and the Universidad\udde Guanajuato, México. Authors are indebted to Dr.\udGuillermo Mendoza-Diaz (Universidad de Guanajuato)\udfor his helpful discussions. The authors thank Salvador\udLópez Morales (Instituto de Investigaciones en Materiales,\udUNAM) for GPC-MALLS analysis. The authors wish\udto thank the Directorate for Research Support and\udPostgraduate Programs at the University of Guanajuato for\udtheir support in the editing of the English-language version\udof this article.Peer Reviewe

Hydrocortisone release from tablets based on bioresorbable poly(ether-ester-urethane)s