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In this study, we evaluated the effects of substitution of partial and total spray-dried blood plasma (BP) with soy protein concentrate (SPC) in the diet of post-weaning piglets on their performance, intestinal histomorphometry, and blood parameters. Fifty-four castrated male piglets, weaned at an average age of 21 days and an initial average weight of 7.01±0.294 kg, were distributed in a completely randomized block design, with three diets (0%SPC-5%BP, 2.5%SPC-2.5%BP, and 5%SPC-0%BP), six replicates, and three piglets per experimental unit. The experimental feeds were formulated to meet the requirements of the piglets at 21-32 and 33-42 days of age (pre-starter diet) and 43-66 days of age (starter diet). From 21 to 32 and 21 to 42 days of age, daily feed intake, daily weight gain, and final weight of the animals were higher in the group fed 2.5%SPC-2.5%BP and 0%SPC-5%BP. From 21 to 66 days of age, daily weight gain and daily feed intake were higher in the animals fed 2.5%SPC-2.5%BP. No effect was observed on the histomorphometry variables. The total leukocyte count was higher in animals fed 2.5%SPC-2.5%BP and 5%SPC-0%BP and the lymphocyte count was lower in the piglets that received 0%SPC-5%BP. The combined use of soy protein concentrate and spray-dried blood plasma in the feeds of piglets between 21 and 42 days of age improves their productive performance

Substitution of blood plasma with soy protein concentrate in piglet diet