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full SDD protocol with parenteral and enteral antimicrobials, assuming that the sample size was sufficient. Opinion leaders have expressed concerns regarding resistance, and, despite the fact that those concerns are based on low level evidence, this has hindered the implementation of SDD. Resistance was not a clinically relevant problem in the 60 RCTs evaluating SDD.

jornal brasileiro de pneumologia

Selective digestive decontamination is superior to oropharyngeal chlorhexidine in preventing pneumonia and reducing mortality in critically ill patients