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A new species of the genus Hypostomus Lacépède (Siluriformes, Loricariidae) from rio Tocantins and rio Xingu basins in central Brazil, is described. The new species is distinguished from its congeners by a unique combination of pale blotches over a darker background on head, body and fins, and conspicuous keels on head, predorsal region and lateral plates. Comments on the pale-spotted species of Hypostomus are provided.Uma nova espécie do gênero Hypostomus Lacépède (Siluriformes, Loricariidae) é descrita das bacias dos rios Tocantins e Xingu no Brasil central. A nova espécie distingue-se de suas congêneres pela combinação única de manchas claras sobre fundo escuro na cabeça, corpo e nadadeiras, e quilhas conspícuas na cabeça, região predorsal e placas laterais. Comentários sobre as espécies de Hypostomus de manchas claras são fornecidos

A new pale-spotted species of Hypostomus Lacépède (Siluriformes: Loricariidae) from the rio Tocantins and rio Xingu basins in central Brazil