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A mensuração dos metabólitos do óxido nítrico pode ser útil para a melhor compreensão de diferentes processos fisiopatológicos. Este estudo avaliou a influência de diferentes anticoagulantes (ácido etilenodiaminotetracético [EDTA], citrato e heparina) e do armazenamento a -20ºC por quatro meses sobre os níveis de nitrito, sendo estes mensurados em amostras de soro e plasma pelo método de Griess. Os tipos de amostra utilizados (soro ou plasma) e de anticoagulante usado na coleta não influenciaram significativamente os níveis de nitrito, independentemente de as dosagens serem realizadas em amostras frescas ou naquelas mantidas a -20ºC por quatro meses. The measurement of nitric oxide metabolites may be useful for better understanding of different physiopathological processes. Thus, the aim of this study was to evaluate the influence of different anticoagulants (EDTA, citrate and heparin) and four-month storage at -20ºC on nitrite levels. The serum and plasma samples were analyzed by using the Griess method. The type of sample (serum or plasma) or anticoagulant used in the collection did not influence on nitrite levels significantly, regardless the fact they were fresh or four-month samples stored at -20ºC

Influência dos anticoagulantes e da temperatura de armazenamento sobre os níveis sanguíneos de nitrito