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INTRODUÇÃO: O lúpus eritematoso sistêmico (LES) é uma doença inflamatória crônica caracterizada por manifestações clínicas variadas. Os poucos trabalhos existentes na literatura relatam uma prevalência entre 6,5% e 21% de acometimento bucal. OBJETIVO: Investigar os achados bucais e laboratoriais em pacientes com LES. MATERIAL E MÉTODO: Foram analisados 155 pacientes com diagnóstico de LES, segundo critérios do American College of Rheumatology (ACR). O índice de dentes cariados, perdidos e obturados (CPO-D) foi registrado e avaliou-se a necessidade de tratamento periodontal por meio do índice periodontal comunitário (IPC). Foram realizados esfregaços e biópsias das lesões e bordas laterais de língua para exames citopatológicos. Exames laboratoriais foram correlacionados com os achados bucais destes pacientes. RESULTADOS: Dos 155 pacientes, 94,1% eram mulheres. Altos níveis de anticorpos circulantes (FAN-Hep2) foram observados em todos os pacientes, sendo 41,9% positivos para a pesquisa de anticorpos anti-DNA de fita dupla. O índice CPO-D médio correspondeu a 18,5 e de acordo com o IPC, 18% apresentaram bolsas periodontais de 4-5 mm e 5,9% de 6 mm ou mais. Foram biopsiadas oito lesões bucais, mas somente três casos foram considerados compatíveis com a indicação clínica de LES. Os principais sítios acometidos foram dorso de língua, mucosa jugal e lábios. A prevalência de candidíase correspondeu a 20,1% e a de leucoplasia pilosa oral a 3,7%. CONCLUSÃO: Pacientes com LES apresentam condição periodontal precária e baixa prevalência de lesões bucais e, além disso, a citopatologia mostrou-se importante no diagnóstico de infecções relacionadas com imunossupressão, como candidíase e leucoplasia pilosa oral. INTRODUCTION: Systemic lupus erythematosus (SLE) is a chronic inflammatory disease, which is characterized by several clinical manifestations. A few studies in the literature state estimated prevalence of 6.5% to 21% in oral manifestations. OBJECTIVE: To investigate the oral and laboratorial findings in patients with SLE. MATERIAL AND METHOD: One hundred fifty-five patients diagnosed with SLE were analyzed in accordance with the American College of Rheumatology (ACR) criteria. The index of decayed, missed and filled teeth (DMFT) was registered and the necessity of periodontal treatment was evaluated by the Community Periodontal Index (CPI). Furthermore, biopsies and smears of the lateral borders of the tongue were performed for cytopathological exams. Laboratory exams were correlated with patients' oral findings. RESULTS: Ninety-four comma one percent of 155 patients were women. High levels of circulating autoantibodies (ANA-Hep2) were observed in all patients and 41.9% of them were positive for anti-double stranded DNA. Mean DMFT index was 18.5. According to CPI, 18% showed periodontal pockets of 4-5 mm and 5.9% pockets of 6mm or more. Eight oral lesions were biopsied, but only three cases were considered compatible with clinical indication of SLE. The main affected sites were dorsum of the tongue, buccal mucosa and lips. The prevalence of candidiasis and oral hairy leucoplakia corresponded to 20.1% and 3.7%, respectively. CONCLUSION: These data suggest that patients with SLE present low prevalence of oral lesions and poor periodontal conditions. Moreover, the cytopathology showed infections associated with immunosuppression such as candidiasis and oral hairy leucoplakia

Achados bucais e laboratoriais em pacientes com lúpus eritematoso sistêmico