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This work describes the in vitro biological properties of three epoxy networks based on diglycidyl ether of glycerol (DGEG) cured with poly(oxypropylene) diamine (D230), isophorone diamine (IPD) and 4,4'- diamino-3,3'-dimethyl-dicyclohexylmethano (3DCM). The biological interactions between epoxy polymers and blood were studied by in vitro assays. Studies of the protein adsorption, platelet adhesion, lactate dehydrogenase (LDH) activity and thromboresistance properties are presented. The protein adsorption assays onto polymeric surfaces showed that the epoxy networks adsorbed more albumin than fibrinogen. The results about platelet adhesion, lactate dehydrogenase (LDH) activity and thromboresistance properties indicated that the DGEG/IPD and DGEG/3DCM networks show hemocompatible behavior. In this way, we can assume that these epoxy polymers are blood compatible materials.

Redes epóxi/amina alifáticas com perspectivas para aplicações cardiovasculares. Propriedades biológicas in vitro