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The species Mikania cordifolia is distributed across America and widely found throughout Brazilian territory, where is popularly used against snake bites. Methanolic and dichloromethanic extracts prepared from M. cordifolia Robinson collected from four different locations in Brazil were submitted to liquid-liquid extraction and the hexanic phase and residues obtained from this step were analyzed for triterpenoids by gas chromatography. The specimens from Ribeirão Preto-SP and São Carlos-SP showed similar triterpenoid composition: alpha-amyrin, lupeol, lupenone, alpha-amyrin acetate, beta-amyrin acetate, lupeol acetate, taraxasterol acetate, campesterol and beta-sitosterol. Besides these triterpenoids, the specimen from Campos de Jordão-SP presented 11-oxours-12-ene, 11-oxoolean-12-ene and taraxerol acetate, and from Monte Verde, epitaraxerol e taraxerol acetate. The triterpene friedelin could be found in specimens from Ribeirão Preto and São Carlos. A espécie Mikania cordifolia distribui-se por toda a América e é amplamente encontrada em quase todo o território brasileiro, onde é utilizada popularmente contra mordidas de serpentes. Extratos metanólicos e diclorometânicos preparados a partir e M. cordifolia Robinson coletadas em quatro locais diferentes do Brasil foram submetidos à extração líquido-líquido e os extratos hexânicos e resíduos obtidos nesta etapa foram analisados para a pesquisa de triterpenóides por cromatografia em fase gasosa. Os espécimes coletados em Ribeirão Preto-SP e São Carlos-SP apresentaram os triterpenóides beta-amirina, lupeol, lupenona, acetato de alfa-amirina, acetato de beta-amirina, acetato de lupeol, acetato de taraxasterol, campesterol e beta-sitosterol na suas composições. Além destes trierpenóides, o espécime de Campos de Jordão-SP apresentou 11-oxours-12-eno, 11-oxoolean-12-eno e acetato de taraxerol e, o de Monte verde-MG, epitaraxerol e acetato de taraxerol. A friedelina foi observada apenas nas amostras de Ribeirão Preto-SP e São Carlos-SP

Comparative analysis of triterpenoids from Mikania cordifolia collected from four different locations