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References 1. Bressan RA, Pilowsky LS. Glutamatergic hypothesis of schizophrenia. Rev Bras Psiquiatr. 2003;25(3):177-83. 2. de Lucena D, Fernandes BS, Berk M, Dodd S, Medeiros DW, Pedrini M, Kunz M, Gomes FA, Giglio LF, Lobato MI, Belmonte-de-Abreu PS, GAMA CS. Improvement of negative and positive symptoms in treatmentrefractory schizophrenia: a double-blind, randomized, placebo-controlled trial with memantine as add-on therapy to clozapine. J Clin Psychiatry. 2009;70(10):1416-23. 3. Peeters M, Page G, Maloteaux JM, Hermans E. Hypersensitivity of dopamine

brazilian journal of psychiatry

High rates of psychiatric disorders in a sample of Brazilian children and adolescents living under social vulnerability - urgent public policies implications