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Levonorgestrel a synthetic progestagen used for endometriosis, dysmenorrhea and emergency contraception, is quickly and completely absorbed in the digestive tract. levonorgestrel is predominantly metabolised through hepatic routes that utilise the CYP3A system (CYP3A4 and CYP3A5).

[Influence of CYP3A4/5 polymorphisms in the pharmacokinetics of levonorgestrel: a pilot study].