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Dois caprinos confinados, que recebiam ração e pasto no cocho, morreram uma semana após serem alimentados com arbustos de plantas de diferentes espécies, entre os quais encontrava-se Trema micrantha. Apenas um animal foi necropsiado. Achados macroscópicos incluíram palidez generalizada da carcaça, hemorragias subcutâneas na região do esterno e escápula, fígado amarelado, friável e com lobulação evidente. Na superfície de corte, o fígado apresentou áreas vermelhas deprimidas entremeadas por áreas claras, deixando na faca, restos de conteúdo amarelado de aspecto gorduroso. Histologicamente, observou-se necrose hepática centrolobular com hemorragia, associada à vacuolização de hepatócitos da região periportal. No encéfalo, havia vacuolização, degeneração e necrose de neurônios do córtex e hipocampo. Os indícios de ingestão da planta associado às lesões hepáticas descritas são compatíveis com intoxicação por Trema micrantha. Two goats which were housed and fed forages and commercial concentrate, died one week after being fed a mixture of plants. Amongst these plant was identified Trema micrantha. Only one animal was necropsied, and paleness of the carcass, subcutaneous haemorrhages in the region of chest and scapula, a yellowish and pliable liver with enhanced lobular pattern were the principal macroscopic findings. Additionally, in the cut surface from the liver, there were reddened and depressed areas mixed with withish ones. The most important histologic findings were hepatic centrilobular necrosis and haemorrhages associated with vacuolization of the periportal hepatocytes. In the encephalic tissue, there were vacuolisation, degeneration and necrosis of the neurones from cortex and hipocampus. The evidences of consumption of the plant and the hepatic lesions here described are consistent findings with the diagnosis of spontaneous poisoning by Trema micrantha

Intoxicação natural por Trema micrantha em caprinos