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Neste trabalho nos descrevemos o uso do ultrassom na sintese de novas naftoquinonas, 6a-f e 7a-c, contendo na posicao 2 do anel quinonoidico substituintes do tipo aminocarboidratos. Estas substâncias foram preparadas, em condicoes brandas, atraves da reacao da 1,4-naftoquinona (8a) ou do metoxi-lapachol (8b) com diferentes aminocarboidratos 9a-d. As estruturas das substâncias foram confirmadas atraves das tecnicas de RMN de 1H e de 13C-APT, uni- e bi-dimensionais (COSY-1H vs. 1H e HETCOR 1JCH), e por espectrometria de massas de alta resolucao com ionizacao por electrospray (ESI MS).

Synthesis of new 2-aminocarbohydrate-1,4-naphthoquinone derivatives promoted by ultrasonic irradiation