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Aromatic aldehydes undergo crossed-aldol condensation with ketones in the presence of silica sulfuric acid under solvent-free conditions to afford the corresponding a, b-unsaturated aldol products in excellent yields. The reagent is reusable for several times without any decrease in the yield of the reactions.

journal of the brazilian chemical society

Silica sulfuric acid as an efficient and reusable reagent for crossed-aldol condensation of ketones with aromatic aldehydes under solvent-free conditions