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<abstract language="eng">A computational interface, using sybyl format as an input file, was created in order to calculate connectivity indexes. After generation and classification of all substructures, which derive from the molecular structure, this interface calculates all possible orders from zero up to the maximun number of bonds in the molecule. Other topological indexes such as Wiener and Schultz indexes can also be calculated

TOP - um programa de cálculo de descritores topológicos para uso em correlações entre estrutura e atividade