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There are several epidemiological, virological and serological lines of evidence suggesting that human herpesvirus 8 (HHV-8) is the cause of Kaposi’s sarcoma (KS) and previous studies have provided evidence for a link between HHV-8 replication and KS pathogenesis. However few prospective studies investigating the relationship between HHV-8 replication and possible risk factors have been published.

Risk factors for human herpesvirus 8 (KSHV/HHV-8) viremia in AIDS patients with Kaposi's sarcoma