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Material and Methods: T. gondii tachyzoites were irradiated with 255 Gy, maintained in nitrogen and freezer. C57Bl/6j mice were immunized with irradiated tachyzoites (3 doses). The humoral and cellular response in immunized mice was analyzed. The immunized mice with 255 Gy irradiated tachyzoites (3 doses) were challenged, by oral route, with ME-49 T. gondii strain, mortality and quantification of cysts number was analyzed.

Evaluation of the cellular and humoral response in mice inoculated with irradiated tachyzoites of Toxoplasma gondii