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It is synthetized the evolution of the researches on myasthenia gravis at the Department of Neurology of the Hospital das Clínicas of the Faculty of Medicine, Medical School of the University of São Paulo (Brazil) between 1950 and 1992. The most important results observed about therapeutical, clinical and pathophysiological researches are reviewed. Immunologic studies and advances on molecular biology are emphasized.

História do estudo da miastenia grave na clínica neurológica do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo