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The chronologic changes of the glucose content in the hemorrahgic cerebrospinal fluid (CSF) in 515 cases have been studied, from the first to the tenth day. A traumatic origin was noticed in 156 cases and 359 were from miscellaneous origin. The diabetes mellitus and the meningitis cases were excluded from the study. The highest glucose content was 245 mg/100 ml and the lowest one was 12 mg/100 ml. The main purpose was to analyse the cases of low glucose levels in the CSF to find out if this would occur in a certain phase of the hemorrhagic event. The conclusions were the following: 1. there was a tendency for high glucose levels in the first few days of the hemorrhagic episode and progressive normalization on the following days: 2. the probability of occuring low glucose levels between the 6th and 8th day of the hemorrhagic event was not confirmed; 3. there were 32 cases with hypoglycorrhachia (6,2% of the total); 4. the intensive xanthochromia that was noticed in all cases with hypoglycorrhachia perhaps would be in behalf of the enzymatic theory and/or the theory of blood-brain barrier block in order to explain these findings.Foi estudada a variação cronológica, do primeiro ao décimo dia, da taxa de glicose no LCR hemorrágico em 515 casos, sendo 156 conseqüente a traumatismos e 359 de outras etiologias. O objetivo principal do trabalho foi o de analisar, em particular, os casos de hipoglicorraquia e de verificar se esta ocorreria preferencialmente em determinado período de evolução do quadro hemorrágico. Os autores chegaram às seguinte conclusões: 1) houve tendência a valores elevados da glicorraquia nos primeiros dias do quadro hemorrágico e progressiva normalização nos dias subseqüentes; 2) a probabilidade da hipoglicorraquia ocorrer entre o 6.° e o 8.° dia do quadro hemorrágico não foi confirmada; 3) foi verificada a ocorrência de 32 casos de hipoglicorraquia, o que corresponde a 6,2% do total; 4) a xantocromia intensa verificada em todos os casos de hipoglicorraquia talvez deponha a favor da teoria enzimática e/ou da teoria do bloqueio da barreira hematoencefálica para a explicação do fato.Escola Paulista de Medicina Departamento de NeurologiaUniversidade de São Paulo Faculdade de Ciências Econômicas e Administrativas Departamento de EstatísticaUNIFESP, EPM, Depto. de NeurologiaSciEL

arquivos de neuro-psiquiatria

Variações da taxa de açúcar no líquido cefalorraqueano em casos de derrame de sangue no espaço sub-aracnóide com especial referência à hipoglicorraquia