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The esophageal carcinoma represents about 2% of malignant tumors and is the third most common cause of gastrointestinal cancer. The correlation between immunohistochemistry markers, such as p53, p16 and COX-2 proteins and cancer esophageal prognosis has been suggested.

Expressão de p53, p16 E COX-2 em carcinoma escamoso de esôfago e associação histopatológica