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Recurrence of hepatitis C after orthotopic liver transplantation is one of the major clinical challenges faced by the liver transplantation community. Treatment of hepatitis C recurrence with peguilated interferon and ribavirin has been associated with sustained virological response in 21% to 45% of treated patients. Furthermore, it has been shown to halt disease progression after orthotopic liver transplantation and to prevent graft failure and the need for retransplantation at least in those subjects with sustained virological response. However, treatment of hepatitis C recurrence after orthotopic liver transplantation in Brazil was not recommended according to ministerial Law number 863.

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Resultado do inquérito nacional sobre condutas no acompanhamento e no tratamento da recurrência da hepatite C em portadores de vírus C submetidos a transplante de fígado National survey about management and treatment options of hepatitis C recurrence after liver transplantation