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Objective:  To determine the total level of flavonoids in brown algae extract  Padina sp .,  Sargassum sp ., and  Turbinaria sp ., which could serve as an analgesic and anti-inflammatory drug.  Material and Methods: This is an experimental study with a one-shot case study research design. The study sample consisted of three species of brown algae, namely,  Padina sp .,  Sargassum sp ., and  Turbinaria sp . The study samples were obtained from Saugi Island, Pangkep, Regency. The sampling method used was convenience sampling. The total flavonoid level in the three extracts of brown algae samples was determined at three concentrations (150 ppm, 300 ppm, and 450 ppm) with three replicates. The analysis used a colorimetric method, a spectrophotometer and aluminium chloride as the reagent .  Results: The total level of flavonoids in  Padina sp . was the highest at 0.894 ± 0.027%, compared to the levels of 0.786 ± 0.075% in  Sargassum sp . and 0.745 ± 0.016% in  Turbinaria sp .  Conclusion: Padina sp . had the highest total flavonoid levels compared to  Sargassum sp . and  Turbinaria sp . Flavonoid compounds from brown algae have the potential to be used as analgesic and anti-inflammatory drugs.

Analysis of the Total Level of Flavonoids in the Brown Algae ( Phaeophyceae ) Extract as Analgesic and Anti-Inflammatory Drugs