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The chemical composition and antifungal activity of the Ageratum conyzoidesessential oils, obtained from the leaves collected in Ibiuna (1), Ribeirao Pires (2) and Campinas (3) in the Sao Paulo state, Brazil, were investigated. The essential oils were obtained from A. conyzoidesleaves by hydrodestilation and analyzed by GC/MS. The chemical composition of the A. conyzoides oil collected in Ribeirao Pires and Ibiuna consisted mainly of precocene I and II. The essential oil from leaves collected in Campinas had only traces of precocene II and a highest proportion of precocene I, α-humulene and (E)-caryophyllene than the oils (1) and (2). The Aspergillus flavus growth was inhibited by essential oils (1) and (2) at 60 and 64%, respectively, and the oil (3) was inactive. On the other hand, the three essential oils inhibited the sporulation of the fungus for more than 120 days. The essential oils of leaves collected in sites that show similarities in the latitude, altitude and average temperatures, as Ribeirao Pires and Ibiuna, showed chemical composition and antifungal activity similar, either, which showed the importance of geo-ecological factors in production of metabolites of the plant.

Fungicidal activity and constituents of Ageratum conyzoides essential oil from three regions in São Paulo state, Brazil