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There has been increasing interest in the study of the association between human mutL homolog 1 (hMLH1) gene polymorphisms and risk of colorectal cancer (CRC). However, results from previous studies are inconclusive. Thus, a meta-analysis was conducted to derive a more precise estimation of the effects of this gene.

revista da associação médica brasileira

Relevance of hMLH1 -93G&gt;A, 655A&gt;G and 1151T&gt;A polymorphisms with colorectal cancer susceptibility: a meta-analysis based on 38 case-control studies